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Sites Menu > Medication Information - Antithrombotics

Medication Information - Antithrombotics

DABIGATRAN (Rendix), A POSSIBLE REPLACEMENT FOR WARFARIN (Coumadin, Jantoven)

Exanta (ximelagatran) had been touted as the replacement for warfarin. However, an FDA Advisory Committee recommended against approval in September 2004. Since that time, dabigatran etexilate has become the rising star of the oral, direct thrombin inhibitor world. Like ximelagatran, dabigatran etexilate is an orally active prodrug. This means that it is not active in the form that is given by mouth, but it is metabolized to the active form dabigatran. For purposes of this review the drug will be simply referred to as dabigatran. Last updated April 8, 2007

Ximelagatran: a new drug to replace warfarin?

Warfarin Institute of America

Low-Molecular-Weight Heparins in Pregnancy

Pharmacotherapy 19(9):1013-1025, 1999. © 1999 Pharmacotherapy Publications

Fragmin SubQ - DALTEPARIN

Dalteparin is used to treat or prevent harmful blood clots. Preventing harmful blood clots helps to reduce the risk of a stroke or heart attack. This medication helps keep your blood flowing smoothly by lowering the activity of clotting proteins in the blood. Dalteparin is a type of heparin, and works as an anticoagulant (commonly called a "blood thinner").

Effects of Unfractionated and Low Molecular Weight Heparin on Antiphospholipid Antibody Binding In Vitro

Obstetrics & Gynecology 2003;101:455-462 © 2003 by The American College of Obstetricians and Gynecologists

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