The Turkish Journal of Pediatrics 2003; 45: 167-169

Science News Online (You May Need To Subscribe To Science News)

Excellent information about the various genetic markers. Includes diagrams.

Copyright © 1996-2006 Dallas Thrombosis Hemostasis Clinical Center

June 2004 Hypercoagulable states, also referred to as thrombophilias or prothrombotic disorders, are disorders that predispose a patient to venous, and sometimes to arterial, thromboembolism. Identification of such conditions may indicate a need for aggressive prophylaxis during high-risk periods, a need for prolonged treatment after an initial episode of thromboembolism, avoidance of oral contraceptives, and investigation of asymptomatic family members when a familial disorder is identified. A prothrombotic disorder should be considered in patients as outlined below. On the other hand, an indiscriminate search for underlying hypercoagulable states is usually unrewarding and may result in false positive results that inappropriately label patients as "clotters". Some hypercoagulable states are associated with late fetal and recurrent pregnancy loss, intrauterine growth retardation and probably other obstetric complications. This guideline will not address this area further as it is rapidly evolving and best management in most situations cannot yet be defined.

Gives Anticoagulation Clinics Locations

Lots of excellent links

Volume 6 Issue 5 Hemaware, Page 13-16

Thrombophilia is a disorder in which the blood clots easily or excessively.

ClotCare strives to help others improve lives by providing both patients and healthcare providers with the most up-to-date information and expert insight on optimal use of antithrombotic and anticoagulant therapy. In achieving this end, ClotCare seeks to be the premier source to which patients and clinicians turn to get information on these therapies used to prevent and/or treat unwanted blood clots that cause heart attacks, strokes, and other potentially catastrophic events.

Travel more than 4 hours carries more risk, whether by plane, train, car, or bus your risk of blood clots with travel is small, but an ounce of prevention is worth a pound of cure! Blood clots can take time to happen after travel, so watch for signs and symptoms of deep vein thrombosis (DVT), a blood clot in your leg, or pulmonary embolism (PE), a blood clot in your lungs. Risk increases with more frequent travel over 4 hours. Travel is great, but you want to prevent blood clots from forming in your legs and traveling to your lungs-this can be deadly in about 1 out of 3 instances.